Medication Side Effects That Can Affect Hearing and Balance

Many common medications can impact your hearing and balance, often without patients or healthcare providers realizing the connection. At Southwest Balance, Dizziness & Ear Institute, we regularly see patients whose hearing loss, tinnitus, or dizziness stems from medications they're taking for completely unrelated health conditions.
Over 200 medications are known to cause hearing or balance problems, ranging from temporary effects that resolve when you stop the medication to permanent damage requiring ongoing treatment. Knowing about these potential side effects helps you make better healthcare decisions and seek help when problems first appear.
Understanding Ototoxicity
Ototoxicity means damage to your ear caused by medications or chemicals. These substances can harm different parts of your ear - the cochlea (which handles hearing), the vestibular system (which controls balance), or both. The damage might happen slowly over months or strike suddenly, depending on which medication you're taking, how much, and personal factors like your kidney function or genetics.
Some medications cause temporary problems that get better once you stop taking them. Others lead to permanent hearing loss or balance issues. Your risk goes up with higher doses, longer treatment periods, and when you're taking multiple ear-damaging medications at the same time.
Common Medications That Affect Hearing
Aminoglycoside antibiotics pose the highest risk for permanent hearing damage. This group includes gentamicin, tobramycin, amikacin, and streptomycin - powerful antibiotics used for serious bacterial infections. While they're excellent at fighting dangerous infections, they can destroy the tiny hair cells in your inner ear, causing high-frequency hearing loss that you might not notice right away.
Loop diuretics, prescribed for heart failure and high blood pressure, can cause temporary hearing loss - especially when given through an IV in high doses. Furosemide (Lasix) tops the list in this category. The hearing loss usually comes back when you stop the medication or lower the dose.
High-dose aspirin and similar medications can trigger tinnitus and hearing loss. If you're taking low-dose aspirin for heart protection, you're probably fine. But people taking higher doses for arthritis or inflammation may run into these problems.
Cancer drugs like cisplatin and carboplatin are notorious for causing permanent hearing loss. Up to 60% of patients getting these treatments lose some hearing, typically starting with high frequencies and potentially progressing to affect normal conversation.
Medications That Impact Balance
Many medications that hurt your hearing can also mess with your balance. The balance organs in your inner ear sit right next to your hearing organs, making them vulnerable to the same toxic effects.
Gentamicin specifically attacks your balance system and doctors sometimes use this effect intentionally to treat severe vertigo - though it permanently destroys balance function. Other aminoglycosides can also affect balance, causing dizziness, unsteadiness, and trouble walking in dim light.
Some seizure medications, like phenytoin (Dilantin), can cause balance problems and dizziness. These effects often relate to dose size and may improve when your doctor adjusts the amount you're taking.
Blood pressure medications can cause dizziness and balance trouble by dramatically lowering your blood pressure, reducing blood flow to your brain and inner ear. While not directly toxic to your ear, these drugs can create symptoms that throw off your stability.
Risk Factors That Increase Vulnerability
Age makes a big difference in medication-related hearing and balance problems. Older adults face higher risk because they often take multiple medications, have declining kidney function that affects how drugs leave their body, and may already have some hearing loss or balance decline.
Your kidney function matters tremendously since many ear-damaging medications exit through your kidneys. When your kidneys aren't working well, these drugs can build up to dangerous levels. Your doctors should check your kidney function before prescribing potentially harmful medications.
Genetics also play a role in your sensitivity to medication-induced hearing loss. Some people carry genetic variations that make them more vulnerable to certain drugs, particularly aminoglycoside antibiotics.
Warning Signs to Watch For
Tinnitus often appears first when medications start damaging your ears. If you develop new ringing, buzzing, or other sounds after starting a medication, call your healthcare provider right away. Catching problems early sometimes prevents permanent damage.
Changes in your hearing - like trouble understanding conversations or sounds seeming muffled - need immediate attention. High-frequency hearing loss typically strikes first, making it harder to hear consonants and understand speech when there's background noise.
Balance symptoms include dizziness, feeling unsteady, difficulty walking in darkness, or sensing that you or your surroundings are spinning. These might develop gradually or appear suddenly.
Prevention and Monitoring Strategies
When your doctor prescribes a potentially ear-damaging medication, get a baseline hearing test before you start treatment. This lets us spot changes early and work with your physician to modify treatment if needed. Regular check-ups during treatment can catch problems before they become serious.
Tell all your healthcare providers about any existing hearing loss or balance problems. This information helps them choose safer medications and adjust doses appropriately.
Never stop prescribed medications on your own, even if you think they're affecting your hearing or balance. Many conditions requiring these medications are life-threatening, and stopping suddenly can be dangerous. Instead, discuss your concerns so doctors can consider alternatives.
The Role of Real Ear Measurements
We use Real Ear Measurements to make sure hearing aids are programmed correctly for each patient's specific hearing loss. This precise fitting becomes even more critical for patients with medication-induced hearing loss, since these cases often involve particular frequency ranges and may change as treatment continues.
Treatment Options When Damage Occurs
If medications have affected your hearing, today's hearing aid technology can often provide significant help. Modern devices are sophisticated enough to address the specific patterns of hearing loss we see with toxic medications, including high-frequency loss and difficulty hearing in noisy places.
For balance problems, vestibular rehabilitation therapy helps your brain compensate for inner ear damage. We work closely with physical therapists who specialize in balance training to create complete treatment plans.
Getting help early usually leads to better results, whether you're dealing with hearing loss, balance problems, or both. The sooner we can evaluate your situation and start appropriate treatment, the better we can help you maintain your quality of life.
Take Action to Protect Your Hearing and Balance
If you're taking medications that could affect your hearing or balance, or if you've noticed changes in either area, don't wait. Our experienced audiologists use advanced testing to identify medication-related hearing and balance problems early, when treatment works best. Call Southwest Balance, Dizziness & Ear Institute at (602) 265-9000 to schedule your evaluation and start protecting your hearing and balance health today.
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Conveniently located near the intersection of 7th Street and Indian School Road.

Southwest Balance, Dizziness & Ear Institute (formerly Arizona Balance & Hearing Aids)
4004 N 7th St.Phoenix, AZ 85014